ImpaQ Ecosystem•Clarivate, Scopus & CORE Data
Clarivate WoS 2024 / 2025 Data
IMPAQ
WoS SCIE Q2Scopus Q1SCImago #8,274Hybrid

ACS Medicinal Chemistry Letters

Acronym:acs
•
Abbreviation (ISO):ACS MED. CHEM. LETT
•
Identifier (ISSN):1948-5875(Print)
•
Publisher:American Chemical Society
Clarivate IF (2026)
3.9↓ -0.1
Journal Impact Factor
IF Trend↓
WoS Quartile
Q2
WoS SCIEJCR Quartile
Clarivate WoS JCR
WoS Categories↓
JCR Release Date: 2026-06-17

Impact Factor Trend (2018–2026)

Clarivate IF trend for ACS Medicinal Chemistry Letters

WoS Q2
23563.7920183.7420193.9820204.3420214.6320224.220233.52024420253.92026
Annual Impact Factor Metric
Current (2026):3.9
Scopus SJR & RankScopus Q1
0.697
#8,274

SCImago Journal Rank citation prestige weighting

Scopus Year: 2025
H-Index (2025)
101

101 papers with at least that number of citations each

WoS: SCIE / JCRQ2
Self-Citation Rate5.7%
Safe Level (< 15%)Warning Level (> 20%)
Self-citation below 15% indicates strong scholarly independence.
Volume & Open AccessHybrid
236articles/year
21.19% Gold OA•100% Original Research

Aims & Scope

ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to: Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics) Biological characterization of new molecular entities in the context of drug discovery Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc. Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic Mechanistic drug metabolism and regulation of metabolic enzyme gene expression Chemistry patents relevant to the medicinal chemistry field.

Topics Covered (Recognized by AI)
Biology88.8%Chemistry85.3%Biochemistry79.7%Medicine79.5%Genetics76.1%Internal medicine55.6%Organic chemistry53.1%Pharmacology45.9%Physics41.4%Stereochemistry31.9%Computer science31.1%Gene30.2%Nuclear magnetic resonance28.5%In vitro28.1%Bioinformatics27.2%Receptor25.4%Combinatorial chemistry24.4%Enzyme23.1%Computational biology21.6%Cell biology20.7%
Primary Research Areas

WoS Categories & Quartiles

Detailed JCR / JCI category rankings and quartile breakdown from Clarivate

Clarivate JCR & JCI
JCRSCIE2026

CHEMISTRY, MEDICINAL

Q2
Rank31/72
IndexSCIE
JCISCIE2026

CHEMISTRY, MEDICINAL

Q2
Rank26/72
IndexSCIE

Annual Historical Statistics & Publications

Track annual publication volume, total citations, and Impact Factor evolution

12 year
2026Latest
IF3.9
Articles / Year340
Total Citations132
2025
IF4
Articles / Year522
Total Citations894
2024
IF3.5
Articles / Year410
Total Citations1,790
2023
IF4.2
Articles / Year363
Total Citations3,247
2022
IF4.632
Articles / Year353
Total Citations3,770

SCImago & Scopus Journal Intelligence

Global SCImago ranking, SJR prestige index, Scopus coverage, and societal policy impact

Rank #8,274Scopus Q1SCImago Profile
Scopus Coverage:2010-2026
Scopus Broad Areas:Biochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and Pharmaceutics
Scopus Citation Rank (SJR)Q1
0.697

Weighted prestige citation metric per document indexed in the Scopus database.

Quartile: Scopus Q1
Citations / Doc (2 years)
2.68

Average citations received per document published in the 2-year window.

2-Year Citation Window
Estimated Publication Fee (APC)
$3,218 USD

Estimated Article Processing Charge for Open Access publication.

Estimated cost / article

Scopus 3-Year Publication & Citation Window

3-Year Citations2,468
3-Year Documents860
Citable Documents740

Aggregated from Scopus database across the 3-year SJR evaluation window.

Societal Impact & Inclusivity (SCImago)

Policy Citations (Overton)0

Citations in government and international policy documents

Female Author Rate37.6%

Percentage of female authors published in the journal

Real-world societal policy reach and author gender diversity tracked by SCImago.

Scopus Subject Categories

Organic ChemistryQ1
BiochemistryQ2
Drug DiscoveryQ2
Academic Metric Intelligence

Journal Metrics & Citation Visualizations

Total Cites vs Self-Cites

Evaluation of scholarly independence and citation reach

Total citations steady growth
Self-citation: 5.7%

Citations per Document

Citation metric windows across 2, 3, and 4 years

Cites / Doc (4 years)Cites / Doc (3 years)Cites / Doc (2 years)

Chinese Academy of Sciences (CAS) Classification

Major / minor zone classification and CAS Early Warning List history

Major Category (Broad Field):
3区 (Zone 3)Medicine
Minor Category (Specific Field):
3区CHEMISTRY, MEDICINAL
CAS Early Warning List History:
Updated annually: 2020 – 2024
2020
Not warned
2021
Not warned
2022
Not warned
2023
Not warned
2024
Not warned

Academic Intelligence Overview & Context

ImpaQ Analysis

ACS Medicinal Chemistry Letters (acronym: acs, abbr: ACS MED. CHEM. LETT, ISSN: 1948-5875) is a peer-reviewed international scholarly journal in the field of CHEMISTRY, published by American Chemical Society in United States since 2010. The periodical holds a Journal Impact Factor (JIF) of 3.90, ranking in quartile Q2 of Web of Science (SCIE), a Scopus SJR indicator of 0.697 (Q1), an H-index of 101.

The journal enforces rigorous peer evaluation with an annual output of approximately 236 scientific articles. In terms of accessibility and author fees, it operates under the Hybrid model with an estimated APC of $3,218 USD. It serves as a benchmark publication platform for academics, researchers, and doctoral candidates seeking global research visibility.

Publishing & Editorial Information

Detailed publisher, peer-review turnaround, and publication cycle specifications

Open Access Model
Hybrid
Publisher
American Chemical Society
Publication Language
English
Frequency
Periodic
Founding Year
2010
Indexing & Databases
SCIEScopusPubMed
Editorial Address
1155 16TH ST, NW, WASHINGTON, USA, DC, 20036

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Record UUID: e01abfea-7d11-45ce-b1bf-d7c84594142d
Database Updated: 2026-10-01